When VisiCalc hit the scene back in the eighties (in the last century), the relatively small group of Apple II users went crazy. It was like manna from heaven for the poor accountants, scientists and engineers who were used to filling in enormous analysis sheets with a pencil. Now, they could use VisiCalc to do the same task, AND calculate the result automatically.
Undoubtedly, spreadsheets can help you improve the efficiency of your company regardless of the nature or size of your business. However, it is very important to note that the process of programming formulae and mathematical algorithms behind spreadsheet programs can be very complex and time consuming; one having to invest much effort to create the most appropriate spreadsheet solution for one's company.
Protection of formulae : How often have you forgotten to protect the cell contains the formula that took you hours to test and perfect. It takes one instance of honest human error, and that formula is gone.
The spreadsheet templates used for business purpose are also complex and these templates are used in stores and other business related affiliates. Profit and loss are mostly dealt with these spreadsheets. Invoice and other deposit related calculations also can be dealt with these spreadsheets.